diff --git a/frigate/api/app.py b/frigate/api/app.py
index cb408b447e..09a459156a 100644
--- a/frigate/api/app.py
+++ b/frigate/api/app.py
@@ -34,7 +34,6 @@ from frigate.api.defs.query.app_query_parameters import AppTimelineHourlyQueryPa
 from frigate.api.defs.request.app_body import (
     AppConfigSetBody,
     MediaSyncBody,
-    ProfileSetBody,
 )
 from frigate.api.defs.tags import Tags
 from frigate.config import FrigateConfig
@@ -244,24 +243,6 @@ def get_active_profile(request: Request):
     return JSONResponse(content={"active_profile": config_obj.active_profile})
 
 
-@router.put("/profile/set", dependencies=[Depends(require_role(["admin"]))])
-def set_profile(request: Request, body: ProfileSetBody):
-    """Activate or deactivate a profile."""
-    profile_manager = request.app.profile_manager
-    err = profile_manager.activate_profile(body.profile)
-    if err:
-        return JSONResponse(
-            content={"success": False, "message": err},
-            status_code=400,
-        )
-    request.app.dispatcher.publish("profile/state", body.profile or "none", retain=True)
-    return JSONResponse(
-        content={
-            "success": True,
-            "active_profile": body.profile,
-        }
-    )
-
 
 @router.get("/ffmpeg/presets", dependencies=[Depends(allow_any_authenticated())])
 def ffmpeg_presets():
diff --git a/frigate/api/camera.py b/frigate/api/camera.py
index cb69a56e3b..c99126e64e 100644
--- a/frigate/api/camera.py
+++ b/frigate/api/camera.py
@@ -23,6 +23,7 @@ from frigate.api.auth import (
     require_camera_access,
     require_role,
 )
+from frigate.api.defs.request.app_body import CameraSetBody
 from frigate.api.defs.tags import Tags
 from frigate.config import FrigateConfig
 from frigate.config.camera.updater import (
@@ -1155,3 +1156,76 @@ async def delete_camera(
         },
         status_code=200,
     )
+
+
+_SUB_COMMAND_FEATURES = {"motion_mask", "object_mask", "zone"}
+
+
+@router.put(
+    "/camera/{camera_name}/set/{feature}",
+    dependencies=[Depends(require_role(["admin"]))],
+)
+@router.put(
+    "/camera/{camera_name}/set/{feature}/{sub_command}",
+    dependencies=[Depends(require_role(["admin"]))],
+)
+def camera_set(
+    request: Request,
+    camera_name: str,
+    feature: str,
+    body: CameraSetBody,
+    sub_command: str | None = None,
+):
+    """Set a camera feature state. Use camera_name='*' to target all cameras."""
+    dispatcher = request.app.dispatcher
+    frigate_config: FrigateConfig = request.app.frigate_config
+
+    if feature == "profile":
+        if camera_name != "*":
+            return JSONResponse(
+                content={
+                    "success": False,
+                    "message": "Profile feature requires camera_name='*'",
+                },
+                status_code=400,
+            )
+        dispatcher._receive("profile/set", body.value)
+        return JSONResponse(content={"success": True})
+
+    if feature not in dispatcher._camera_settings_handlers:
+        return JSONResponse(
+            content={"success": False, "message": f"Unknown feature: {feature}"},
+            status_code=400,
+        )
+
+    if sub_command and feature not in _SUB_COMMAND_FEATURES:
+        return JSONResponse(
+            content={
+                "success": False,
+                "message": f"Feature '{feature}' does not support sub-commands",
+            },
+            status_code=400,
+        )
+
+    if camera_name == "*":
+        cameras = list(frigate_config.cameras.keys())
+    elif camera_name not in frigate_config.cameras:
+        return JSONResponse(
+            content={
+                "success": False,
+                "message": f"Camera '{camera_name}' not found",
+            },
+            status_code=404,
+        )
+    else:
+        cameras = [camera_name]
+
+    for cam in cameras:
+        topic = (
+            f"{cam}/{feature}/{sub_command}/set"
+            if sub_command
+            else f"{cam}/{feature}/set"
+        )
+        dispatcher._receive(topic, body.value)
+
+    return JSONResponse(content={"success": True})
diff --git a/frigate/api/defs/request/app_body.py b/frigate/api/defs/request/app_body.py
index 1640da739a..45392a1380 100644
--- a/frigate/api/defs/request/app_body.py
+++ b/frigate/api/defs/request/app_body.py
@@ -30,10 +30,8 @@ class AppPutRoleBody(BaseModel):
     role: str
 
 
-class ProfileSetBody(BaseModel):
-    profile: Optional[str] = Field(
-        default=None, description="Profile name to activate, or null to deactivate"
-    )
+class CameraSetBody(BaseModel):
+    value: str = Field(..., description="The value to set for the feature")
 
 
 class MediaSyncBody(BaseModel):
diff --git a/web/src/components/menu/GeneralSettings.tsx b/web/src/components/menu/GeneralSettings.tsx
index 7353a30359..dfe39be470 100644
--- a/web/src/components/menu/GeneralSettings.tsx
+++ b/web/src/components/menu/GeneralSettings.tsx
@@ -128,7 +128,7 @@ export default function GeneralSettings({ className }: GeneralSettingsProps) {
 
   const handleActivateProfile = async (profileName: string | null) => {
     try {
-      await axios.put("profile/set", { profile: profileName || null });
+      await axios.put("camera/*/set/profile", { value: profileName ?? "none" });
       await updateProfiles();
       toast.success(
         profileName
diff --git a/web/src/views/settings/ProfilesView.tsx b/web/src/views/settings/ProfilesView.tsx
index b9c00b6d5d..3c44360156 100644
--- a/web/src/views/settings/ProfilesView.tsx
+++ b/web/src/views/settings/ProfilesView.tsx
@@ -207,8 +207,8 @@ export default function ProfilesView({
     async (profile: string | null) => {
       setActivating(true);
       try {
-        await axios.put("profile/set", {
-          profile: profile || null,
+        await axios.put("camera/*/set/profile", {
+          value: profile ?? "none",
         });
         await updateProfiles();
         toast.success(
@@ -244,7 +244,7 @@ export default function ProfilesView({
     try {
       // If this profile is active, deactivate it first
       if (activeProfile === deleteProfile) {
-        await axios.put("profile/set", { profile: null });
+        await axios.put("camera/*/set/profile", { value: "none" });
       }
 
       // Remove the profile from all cameras and the top-level definition